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A mode of action for induction of thyroid gland tumors by Pyrethrins in the rat

✍ Scribed by John M. Finch; Thomas G. Osimitz; Karl L. Gabriel; Tom Martin; Wendy J. Henderson; Charles C. Capen; William H. Butler; Brian G. Lake


Book ID
113923866
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
620 KB
Volume
214
Category
Article
ISSN
0041-008X

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Mycotoxins and the kidney: Modes of acti
✍ Angela Mally; Wolfgang Dekant πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 843 KB

## Abstract The mycotoxin ochratoxin A (OTA) is a potent renal carcinogen in rodents. OTA is only slowly eliminated due to high affinity to plasma proteins and inefficient biotransformation. A number of mechanisms have been proposed to account for renal tumor formation. DNA adduct formation, mainly