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A mixture of benzene metabolites produces a synergistic increase in aneuploidy in cultured human lymphocytes

✍ Scribed by M.T. Smith; M.L. Robertson; D.A. Eastmond


Book ID
113252206
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
171 KB
Volume
252
Category
Article
ISSN
0165-1161

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Benzene increases aneuploidy in the lymp
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Benzene is an established human leukemogen that increases the level of chromosome aberrations in lymphocytes of exposed workers. Numerical aberrations (aneusomy) can be observed by fluorescence in situ hybridization (FISH) in both interphase and metaphase cells. Whereas interphase FISH allows nondiv