A Markov mixed effect regression model f
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Pascal Girard; Terrence F. Blaschke; Helen Kastrissios; Lewis B. Sheiner
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Article
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1998
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John Wiley and Sons
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English
β 261 KB
π 2 views
Patient compliance (adherence) with prescribed medication is often erratic, while clinical outcomes are causally linked to actual, rather than nominal medication dosage. We propose here a hierarchical Markov model for patient compliance. At the first stage, conditional upon individual random effects