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A Missense Mutation of Cardiac β-Myosin Heavy Chain Gene Linked to Familial Hypertrophic Cardiomyopathy in Affected Japanese Families

✍ Scribed by H. Harada; A. Kimura; H. Nishi; T. Sasazuki; H. Toshima


Book ID
115573273
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
532 KB
Volume
194
Category
Article
ISSN
0006-291X

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Familial hypertrophic cardiomyopathy is a genetically heterogeneous disease in which one of the most frequently implicated gene is the gene encoding the b-myosin heavy chain. To date, more than 40 distinct mutations have been found within this gene. In order to progress on the determination of genot