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A minor subset of HLA-DR3 haplotypes is preferentially increased in Type 1 (insulin-dependent) diabetes

✍ Scribed by M. J. Sheehy; J. R. Rowe; T. C. Fuller; E. J. Yunis; K. H. Gabbay

Publisher
Springer
Year
1985
Tongue
English
Weight
450 KB
Volume
28
Category
Article
ISSN
0012-186X

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We analyzed 88 unrelated subjects with Type 1 (insulin-dependent) diabetes and 64 sibling controls (maximum one per diabetic) for associations between immunoglobulin allotype antigens (GM and KM) and Type 1 diabetes. None were found. However, we did find interactions between GM, HLA-DR, and Type 1 d