Computation of the Uniform Minimum Varia
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Scott S. Emerson
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Article
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1993
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Elsevier Science
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English
โ 182 KB
The sampling distribution of data collected in a group sequential trial is such that the usual fixed-sample estimates of treatment effect are biased. Improved estimates can be obtained by taking the group sequential stopping rule into account. In particular, in the case of inference about the mean o