A sensitive and specific LC-MS/MS assay for the determination of paclitaxel and its 3'p- and 6-alpha-hydroxy metabolites is presented. A 200 microL plasma aliquot was spiked with a 13C6-labeled paclitaxel internal standard and extracted with 1.0 mL tert-butylmethylether. Dried extracts were reconsti
✦ LIBER ✦
A miniaturized membrane inlet mass spectrometry interface for analysis of nitric oxide in human plasma
✍ Scribed by Eugenia V. Trushina; Nigel J. Clarke†; Linda M. Benson; Andy J. Tomlinson; Cynthia T. McMurray; Stephen Naylor
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 404 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0951-4198
No coin nor oath required. For personal study only.
✦ Synopsis
Figure 3. The release of NO-treated plasma after the addition of HgCl 2 in 2 M HCl. Analysis was performed as described in the legend for Fig. 2. The very first injection (À1) represents a blank injection of water before introducing NO.
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