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A microwave-assisted, copper-catalyzed three-component synthesis of dihydropyrimidinones under mild conditions

✍ Scribed by Kalyan Kumar Pasunooti; Hua Chai; Chantel Nixon Jensen; Bala Kishan Gorityala; Siming Wang; Xue-Wei Liu

Book ID: 104098542
Publisher: Elsevier Science
Year: 2011
Tongue: French
Weight: 356 KB
Volume: 52
Category: Article
ISSN: 0040-4039
DOI: 10.1016/j.tetlet.2010.10.150

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✦ Synopsis

The synthesis of dihydropyrimidinones via a clean multi-component Biginelli reaction under microwave irradiation is reported. The copper-catalyzed process proved to be simple, efficient, economical, and environmentally friendly.

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