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A microsurgical technique for simultaneous pancreas and renal transplantation in the rat

✍ Scribed by Michael Stephen Nolan; Nigel Jonathan Lindsey; Nicholas Paul Ingram; Alice Herold; David Norman Slater; Miles Fox


Publisher
John Wiley and Sons
Year
1984
Tongue
English
Weight
564 KB
Volume
5
Category
Article
ISSN
0738-1085

No coin nor oath required. For personal study only.

✦ Synopsis


A successful technique of simultaneous pancreatico-renal transplantation into the streptozotocin-induced diabetic rat is described employing a sutureless cuff technique for three of four vascular anastomoses. Reversal of the diabetic state was uniformly observed within 24 hours postoperatively and near-normal renal function was evidenced by 50 days postoperatively. The technique is reliable and reproducible and represents the first report of successful combined transplantation into the diabetic rat.


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