Achievement of high cell density and hig
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Jeng-Dar Yang; Yale Angelillo; Mina Chaudhry; Cindy Goldenberg; David M. Goldenb
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Article
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2000
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John Wiley and Sons
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English
β 264 KB
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Controlled feeding of nutrient supplements to a cell culture to enhance monoclonal antibody productivity has been practiced widely in high-yield, fed-batch processes. In this study, a similar feeding concept has been applied to a perfused culture and evaluated for the effects on bioreactor productiv