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A microelectronic DNA chip detects the V617F JAK-2 mutation in myeloproliferative disorders

✍ Scribed by Di Ianni, M; Moretti, L; Del Papa, B; Gaozza, E; Bell, A S; Falzetti, F; Tabilio, A

Book ID
110056876
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
193 KB
Volume
20
Category
Article
ISSN
0887-6924

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The V617F JAK2 mutation and the myelopro
The V617F JAK2 mutation and the myeloproliferative disorders
✍ Melanie J Percy; Mary Frances McMullin πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 70 KB

## Abstract The discovery this year of a single mutation in the Janus Kinase (__JAK__)‐2 gene in a high percentage of cases of polycythaemia vera (PV), essential thrombocythaemia (ET) and myelofibrosis suggests that it maybe the underlying molecular mechanism for these disorders. Different approach