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A microdialysis study of glutamate concentration in the hippocampus of rats after TsTX toxin injection and blockade of toxin effects by glutamate receptor antagonists

✍ Scribed by Ana Leonor A Nencioni; Ivo Lebrun; Valquiria A.C Dorce

Book ID
114102776
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
345 KB
Volume
74
Category
Article
ISSN
0091-3057

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## Abstract Using microdialysis in CA1 of the rat hippocampus, we studied the effect of transient cerebral ischemia on in vivo uptake and on extracellular levels of glutamate during, and at different time points after ischemia. ^3^H‐D‐aspartate (test substance), and ^14^C‐mannitol (reference substa