A microarray study of altered gene expression in colorectal cancer cells after treatment with immunomodulatory drugs: differences in action in vivo and in vitro

Enhanced in vitro invasiveness and drug

Enhanced in vitro invasiveness and drug resistance with altered gene expression patterns in a human lung carcinoma cell line after pulse selection with anticancer drugs

✍ Yizheng Liang; Lorraine O'Driscoll; Susan McDonnell; Padraig Doolan; Irene Ogles 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 French ⚖ 637 KB

## Abstract The human lung carcinoma cell line DLKP was exposed to sequential pulses of 10 commonly used chemotherapeutic drugs (VP‐16, vincristine, taxotere, mitoxantrone, 5‐fluorouracil, methotrexate, CCNU, BCNU, cisplatin and chlorambucil); resulting cell lines exhibited resistance to the select