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A microarray-based system for the simultaneous analysis of single nucleotide polymorphisms in human genes involved in the metabolism of anti-malarial drugs

✍ Scribed by Eva Maria Hodel, Serej D Ley, Weihong Qi, Frédéric Ariey, Blaise Genton…

Book ID
120686997
Publisher
BioMed Central
Year
2009
Tongue
English
Weight
963 KB
Volume
8
Category
Article
ISSN
1475-2875

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## Communicated by Pui-Yan Kwok A class of genes, known as drug metabolism enzymes (DMEs) are responsible for the metabolism and transport of drugs and other xenobiotics. Variation in DME genes most likely accounts for a proportion of the variability in drug response in humans, and may contribute