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A methodology for construction of a multivariate diagnostic instrument: An application to alcohol abuse screening

✍ Scribed by Robert R. Rawlings; Donald S. Rae; Barry I. Graubard; Michael J. Eckardt; Ralph S. Ryback

Book ID: 103053176
Publisher: Elsevier Science
Year: 1982
Tongue: English
Weight: 814 KB
Volume: 15
Category: Article
ISSN: 0010-4809
DOI: 10.1016/0010-4809(82)90058-1

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✦ Synopsis

A methodology for the implementation of a computerized medical diagnostic instrument utilizing quadratic discriminant functions is presented. The emphasis of the methodology is the careful mathematical modeling and the determination of sample sizes required for a good diagnostic instrument. An attempt is made to present, in detail, the practical mathematical modelin difficulties involved in developing a quadratic (or linear) classification function and some methods for avoiding these difficulties. The methodology discussed involves the use of a stepwise quadratic discriminant procedure. as well as statistical simulation. and an application to alcohol abuse screening.

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