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A method usingL/CMS for determination of absolute configuration of constituent amino acids in peptide --- advanced Marfey's method ---

โœ Scribed by Ken-ichi Harada; Kiyonaga Fujii; Tsuyoshi Mayumi; Yasuko Hibino; Makoto Suzuki; Yoshitomo Ikai; Hisao Oka


Publisher
Elsevier Science
Year
1995
Tongue
French
Weight
215 KB
Volume
36
Category
Article
ISSN
0040-4039

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## Abstract Enantiopure ฮฑโ€amino acids were converted to 4โ€substituted 2โ€arylโ€ and 2โ€alkylโ€5(4__H__)โ€oxazolones under partial racemization. These nonracemic mixtures were dissolved in CDCl~3~, an equimolar amount of the chiral dirhodium complex $Rh^{\rm (II)}\_{2}$[(__R__)โˆ’ (+)โˆ’ MTPA]~4~ (MTPAโ€H = M