## Abstract In the last decade, numerous genomeβwide linkage and association studies of complex diseases have been completed. The critical question remains of how to best use this potentially valuable information to improve study design and statistical analysis in current and future genetic associa
β¦ LIBER β¦
A method to incorporate prior information into score test for genetic association studies
β Scribed by Zakharov, Sergii; Teoh, Garrett HK; Salim, Agus; Thalamuthu, Anbupalam
- Book ID
- 121561160
- Publisher
- BioMed Central
- Year
- 2014
- Tongue
- English
- Weight
- 417 KB
- Volume
- 15
- Category
- Article
- ISSN
- 1471-2105
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## Abstract Multiple testing is a challenging issue in genetic association studies using large numbers of single nucleotide polymorphism (SNP) markers, many of which exhibit linkage disequilibrium (LD). Failure to adjust for multiple testing appropriately may produce excessive false positives or ov