✦ LIBER ✦

A Method of Gene-Function Annotation Based on Variable Precision Rough Sets

✍ Scribed by Zhi-li Pei; Xiao-hu Shi; Meng Niu; Xu-ning Tang; Li-sha Liu; Ying Kong; Yan-chun Liang

Publisher: SciencePress (China)
Year: 2007
Tongue: English
Weight: 200 KB
Volume: 4
Category: Article
ISSN: 1672-6529
DOI: 10.1016/s1672-6529(07)60030-4

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✦ Synopsis

It is very important in the field of bioinformatics to apply computer to perform the function annotation for new sequenced bio-sequences. Based on GO database and BLAST program, a novel method for the function annotation of new biological sequences is presented by using the variable-precision rough set theory. The proposed method is applied to the real data in GO database to examine its effectiveness. Numerical results show that the proposed method has better precision, recall-rate and harmonic mean value compared with existing methods.

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