A method for three-dimensional time-resolved optical tomography

✍ Scribed by Simon R. Arridge; Jeremy C. Hebden; Martin Schweiger; Florian E.W. Schmidt; Martin E. Fry; Elizabeth M.C. Hillman; Hamid Dehghani; David T. Delpy

• Publisher: John Wiley and Sons
• Year: 2000
• Tongue: English
• Weight: 805 KB
• Volume: 11
• Category: Article
• ISSN: 0899-9457
• DOI: 10.1002/(sici)1098-1098(2000)11:1<2::aid-ima2>3.0.co;2-j

✦ Synopsis

We present an overview of time-resolved optical tomography together with the hardware and software methods that we have developed for a clinical instrument that implements this modality. The hardware is based on a multichannel photon-counting technique that records the histograms of photons time-of-flight through highly scattering and attenuating media. The software is based on a finite element model that is iteratively updated in order to minimize the difference between measured and modeled data. We have presented a first experimental reconstruction of a three-dimensional (3D) distribution of variable absorption and scattering coefficient, together with an ideal simulation of the same case.