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A method for the synthesis of racemic and optically active 2-substituted 9-(2′,3′-dihydroxypropyl)-8-azahypoxanthines and 8-azaadenines

✍ Scribed by P. L. Barili; G. Biagi; I. Giorgi; O. Livi; V. Scartoni


Book ID
112130098
Publisher
Journal of Heterocyclic Chemistry
Year
1991
Tongue
English
Weight
362 KB
Volume
28
Category
Article
ISSN
0022-152X

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Preparation of new N6, 9-disubstituted 2
✍ Giuliana Biagi; Irene Giorgi; Oreste Livi; Federica Pacchini; Valerio Scartoni; 📂 Article 📅 2004 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 160 KB

## Abstract A suitably substituted pyrimidine **1** was converted to a number of title compounds. Nucleophilic substitu tion involving the chlorine atoms in **1** by treatment with phenylmethanethiol yielded **2** or **3**, depending on the reaction temperature. Treatment of **3** with an amine aff