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A method for the stereospecific synthesis of trisubstituted olefins by 1,5-prototropic shift

โœ Scribed by E.J. Corey; David K. Herron


Publisher
Elsevier Science
Year
1971
Tongue
French
Weight
115 KB
Volume
12
Category
Article
ISSN
0040-4039

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Highly reactive equivalents of allyliden
โœ E.J. Corey; Manoj C. Desai ๐Ÿ“‚ Article ๐Ÿ“… 1985 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 186 KB

Ylides derived from 3-dimethylaminopropyltriphenylphosphonium salts react smoothly and stereospecifically with even hindered aldehydes to form Z-oletis which are easily converted to 1,3-dienes. In connection with research which recently led to the total synthesis of (+)-retigeranic acid, 1 we had