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A method for the determination of volatile organic acids in aqueous solutions and urine, and the results obtained in propionic acidaemia, β-methylcrotonylglycinuria and methylmalonic aciduria

✍ Scribed by Ronald A. Chalmers; Sheila Bickle; R.W.E. Watts


Book ID
115820517
Publisher
Elsevier Science
Year
1974
Tongue
English
Weight
726 KB
Volume
52
Category
Article
ISSN
0009-8981

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The identification of (E)-2-methylglutac
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The identification of (E)-2-methylglutaconic acid, a 'new' metabolite of isoleucine, is described. The substance was detected in urine samples from patients with propionic acidaemia, methylmalonic acidaemia and so-called P-ketothiolase deficiency; in the majority of cases together with N-tiglylglyci