A method for systematic assessment of the relative prognostic significance of symptoms and signs in patients with a chronic disease: I. Description of model and selection of prognostically significant symptoms and signs

✍ Scribed by P. Winkel; K. Lyngborg; K.H. Olesen; J. Meibom; P.Fritz Hansen

• Publisher: Elsevier Science
• Year: 1972
• Tongue: English
• Weight: 411 KB
• Volume: 5
• Category: Article
• ISSN: 0010-4809
• DOI: 10.1016/0010-4809(72)90062-6

✦ Synopsis

A model of the course of a chronic disease was formulated. The model implies that among patients suffering from a chronic disease a symptom or sign relevant to the prognosis will be present more frequently the earlier it occurs in the natural course of the disease.

Utilizing this principle a method for the assessment of the relative prognostic significance of symptoms and signs was derived.

The results of its application on the data from a series of patients with aortic incompetence were in accordance with the model and proved to b-e clinically meaningful.