𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A method for studying cerebral vascular tone variations in animals

✍ Scribed by T. Iu. Liberman


Publisher
Springer US
Year
1958
Tongue
English
Weight
606 KB
Volume
45
Category
Article
ISSN
0007-4888

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Both a mixture likelihood method and the EM algorithm are implemented to estimate the time-toonset-of and the time-to-death-from the tumor of interest in animal carcinogenicity studies. Both methods are implemented using Box's Complex Method for ΓΏnding the maximum likelihood estimates of parameters