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A method for simultaneous recording of electrical activities and spectrophotometric signals from brain slice preparations in vitro

✍ Scribed by Takanori Fujii; Ken'ichi Toita


Publisher
Springer
Year
1991
Tongue
English
Weight
388 KB
Volume
419
Category
Article
ISSN
0031-6768

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✦ Synopsis


Organ spectrophotometry has been applied to analyze cytochrome redox changes in brain slice preparations. An interface-chamber method for maintaining metabolism of brain slice tissues was devised toreduce noise on recording traces of spectrophotometric signals, and then used for continuous monitoring and simultaneous recording of electrical and optical signals from brain slices. With this method, the noise level during the recording of redox states of cytochromes was decreased to 0.0004 A unit.