The absolute configuration of beta-hydroxy-alpha-amino acids was studied by CD exciton chirality method using 7-diethylaminocoumarin-3-carboxylate as a red-shifted chromophore. The CD spectra of bischromophoric derivatives of (S)-serine and (2S,3R)-threonine methyl esters (2 and 7) were compared wit
A method for determination of the absolute stereochemistry of α,β-epoxy alcohols derived from fatty acid hydroperoxides
✍ Scribed by Mats Hamberg
- Book ID
- 112773662
- Publisher
- Springer-Verlag
- Year
- 1992
- Tongue
- English
- Weight
- 604 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0024-4201
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Aromatic B-amino acids were converted to the Dnp derivatives, and aliphatic ones to Dnp-pMA derivatives. The sign of the Cotton effect near 400 nm reflected the configuration at the B-position without exception. Thus, the relation seems to afford a new reliable method for determining the absolute
## Abstract Enantiopure α‐amino acids were converted to 4‐substituted 2‐aryl‐ and 2‐alkyl‐5(4__H__)‐oxazolones under partial racemization. These nonracemic mixtures were dissolved in CDCl~3~, an equimolar amount of the chiral dirhodium complex $Rh^{\rm (II)}\_{2}$[(__R__)− (+)− MTPA]~4~ (MTPA‐H = M