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A method for detecting epistasis in genome-wide studies using case-control multi-locus association analysis

✍ Scribed by Javier Gayán; Antonio González-Pérez; Fernando Bermudo; María Eugenia Sáez; Jose Luis Royo; Antonio Quintas; Jose Jorge Galan; Francisco Jesús Morón; Reposo Ramirez-Lorca; Luis Miguel Real; Agustín Ruiz

Book ID
115004693
Publisher
BioMed Central
Year
2008
Tongue
English
Weight
297 KB
Volume
9
Category
Article
ISSN
1471-2164

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## Abstract The large number of markers considered in a genome‐wide association study (GWAS) has resulted in a simplification of analyses conducted. Most studies are analyzed one marker at a time using simple tests like the trend test. Methods that account for the special features of genetic associ