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A method for administration of prolonged intravenous infusion of prostacyclin (PGI2) to unanesthetized rats

✍ Scribed by James R. Weeks


Book ID
119048785
Publisher
Elsevier Science
Year
1979
Tongue
English
Weight
341 KB
Volume
17
Category
Article
ISSN
0090-6980

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Dose-independent pharmacokinetics of a c
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Dose-independent pharmacokinetic parameters of SR-4668 were observed after intravenous (i.v.) administrations at doses of 25, 50, and 75 mg/kg and oral administrations at doses of 50, 100, and 150 mg/kg to rats. The hepatic, gastric, and intestinal first-pass effects of SR-4668 were also measured af