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A metallomics approach discovers selenium-containing proteins in selenium-enriched soybean

✍ Scribed by Qilin Chan; Joseph A. Caruso


Book ID
113022021
Publisher
Springer
Year
2012
Tongue
English
Weight
517 KB
Volume
403
Category
Article
ISSN
1618-2650

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## Abstract We found that ebselen [2‐phenyl‐1,2‐benzisoselenazol‐3(2H)‐one] caused phosphorylation of mitogen‐activated protein kinase (MAPK), followed by expression of neurofilament‐M, a neuron‐specific protein, in cultured PC12 rat pheochromocytoma cells. The ebselen‐induced MAPK activation was s