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A membrane protein required for dislocation of misfolded proteins from the ER

✍ Scribed by Lilley, Brendan N.; Ploegh, Hidde L.


Book ID
109892954
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
512 KB
Volume
429
Category
Article
ISSN
0028-0836

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## Abstract In this study, free‐energy function (FEF) for discriminating the native fold of a protein from misfolded decoys was investigated. It is a physics‐based function using an all‐atom model, which comprises the hydration entropy (HE) and the total dehydration penalty (TDP). The HE is calcula