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A mechanistic study of the photooxidation of A2E, a component of human retinal lipofuscin

โœ Scribed by E.R. Gaillard; L.B. Avalle; L.M.M. Keller; Z. Wang; K.J. Reszka; J.P. Dillon

Book ID
116456002
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
173 KB
Volume
79
Category
Article
ISSN
0014-4835

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## Abstract A recent study in vitro demonstrated that a major lipofuscin component, A2E, serves as a retinoic acid receptor ligand. The current study investigated the effects of A2E on retinal pigment epithelial (RPE) cells in vivo and was performed to extend the understanding of the effects of A2E