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A mechanism of S-(1,2,3,4,4-pentachloro-1,3-butadienyl)-l-cysteine toxicity to rabbit renal proximal tubules

โœ Scribed by Rick G. Schnellmann; Edward A. Lock; Lazaro J. Mandel


Book ID
113206941
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
801 KB
Volume
90
Category
Article
ISSN
0041-008X

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The relationship between the covalent binding, uptake, and toxicity produced by S-(1,2-dichlorovinyl)-L-cysteine (DCVC) and S-(1,1,2,2-tetrafluoroethyl)-L-cysteine (TFEC) was investigated in suspensions of rabbit renal proximal tubules (RPT). The DCVC and TFEC at concentrations of 25 pM produced a t