A mechanism for Ikaros regulation of human globin gene switching
โ Scribed by Janelle R. Keys; Michael R. Tallack; Ye Zhan; Peter Papathanasiou; Christopher C. Goodnow; Karin M. Gaensler; Merlin Crossley; Job Dekker; Andrew C. Perkins
- Book ID
- 108675681
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 753 KB
- Volume
- 0
- Category
- Article
- ISSN
- 0007-1048
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We describe three strategies for the identification of specific cis and trans factors that regulate globin gene expression, all three of which are based on the evolution of the globin genes and their expression patterns. The first approach, phylogenetic footprinting, relies on a search for sequence
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