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A mechanical explanation of RNA pseudoknot function in programmed ribosomal frameshifting

✍ Scribed by Namy, Olivier; Moran, Stephen J.; Stuart, David I.; Gilbert, Robert J. C.; Brierley, Ian

Book ID
109895826
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
317 KB
Volume
441
Category
Article
ISSN
0028-0836

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## Abstract Many viruses reprogram ribosomes to produce two different proteins from two different reading frames. So‐called βˆ’1 frameshifting often involves pairwise alignment of two adjacent tRNAs at a β€˜slippery' sequence in the ribosomal A and P sites such that an overlapping codon is shifted upst