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A mathematical model of evolution of biological populations

โœ Scribed by B. B. Dunaev


Publisher
Springer US
Year
1990
Tongue
English
Weight
512 KB
Volume
26
Category
Article
ISSN
1573-8337

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โœ TOMOYUKI MIURA; PIERRE SONIGO ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 207 KB

The purpose of this paper is to determine the optimal mutation rate for random mutagenesis procedures used to make mutant libraries for subsequent screening. When the mutation rate is low, the probability of achieving a rare beneficial mutation is low. When the mutation rate is high, the probability