A Mathematical Model of Cell Cycle Effects in Gastric Cancer Chemotherapy
β Scribed by Rachel Roe-Dale; David Isaacson; Michael Kupferschmid
- Book ID
- 107386231
- Publisher
- Springer
- Year
- 2011
- Tongue
- English
- Weight
- 618 KB
- Volume
- 74
- Category
- Article
- ISSN
- 1522-9602
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The evolution of the cell-cycle is known to be influenced by environmental conditions, including lack of extracellular oxygen (hypoxia). Notably, hypoxia appears to have different effects on normal and cancer cells. Whereas both experience hypoxia-induced arrest of the G 1 phase of the cell-cycle (i
The effects of preoperative chemotherapy on gastric and colonic cancers have yet to be evaluated fully. In this study, its effects were assessed by studying DNA ploidy patterns, cell cycles, and histological findings in such patients. Thirty-nine patients with gastric or colonic cancer were given pr