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A mathematical model for the spray freeze drying process: The drying of frozen particles in trays and in vials on trays

โœ Scribed by A.I. Liapis; R. Bruttini


Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
566 KB
Volume
52
Category
Article
ISSN
0017-9310

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Modeling of the primary and secondary dr
โœ P. Sheehan; A. I. Liapis ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 510 KB

A rigorous unsteady state and spatially multidimensional model is presented and solved to describe the dynamic behavior of the primary and secondary drying stages of the lyophilization of a pharmaceutical product in vials for different operational policies. The results in this work strongly motivate