A Mathematical Model for Experimental Ge
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TOMOYUKI MIURA; PIERRE SONIGO
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Article
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2001
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Elsevier Science
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English
β 207 KB
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The purpose of this paper is to determine the optimal mutation rate for random mutagenesis procedures used to make mutant libraries for subsequent screening. When the mutation rate is low, the probability of achieving a rare beneficial mutation is low. When the mutation rate is high, the probability