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A Mass Spectrometry Plate Reader: Monitoring Enzyme Activity and Inhibition with a Desorption/Ionization on Silicon (DIOS) Platform

โœ Scribed by Zhouxin Shen; Eden P. Go; Alejandra Gamez; Junefredo V. Apon; Valery Fokin; Mike Greig; Manuel Ventura; John E. Crowell; Ola Blixt; James C. Paulson; Raymond C. Stevens; M. G. Finn; Gary Siuzdak


Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
197 KB
Volume
5
Category
Article
ISSN
1439-4227

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## Abstract Desorption/ionization on porous silicon (DIOS) is a form of laser desorption mass spectrometry that allows for the direct mass analysis of a variety of analytes without the addition of organic matrix. Protocols are described for the direct analysis of exocrine tissue and single neurons