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A mass spectrometric investigation of the binding of gold antiarthritic agents and the metabolite [Au(CN)2]−to human serum albumin

✍ Scribed by Jihan Talib; Jennifer L. Beck; Stephen F. Ralph

Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
340 KB
Volume
11
Category
Article
ISSN
1432-1327

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Proton relaxation enhancement (PRE) values for fatty acid spin labels bound to human serum albumin have been investigated using the inversion-recovery method at 24 MHz. At 0.1 mM protein concentration and a label-to-protein ratio of one-to-one, the PRE value for 12-Doxylsterate-albumin complex is 7.