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A major allergen gene-fusion protein for potential usage in allergen-specific immunotherapy

✍ Scribed by Kussebi, Fatimah; Karamloo, Fariba; Rhyner, Claudio; Schmid-Grendelmeier, Peter; Salagianni, Maria; Mannhart, Christian; Akdis, Mübeccel; Soldatova, Lyudmilla; Markovic-Housley, Zora; von Beust, Barbara R.; Kündig, Thomas; Kemeny, David M.; Blaser, Kurt; Crameri, Reto; Akdis, Cezmi A.

Book ID
119274875
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
258 KB
Volume
115
Category
Article
ISSN
1097-6825

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Detection of a recessive major gene for
Detection of a recessive major gene for high IgE levels acting independently of specific response to allergens
✍ M. H. Dizier; M. Hill; A. James; J. Faux; G. Ryan; P. le Souef; M. Lathrop; A. W 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 720 KB

The genetic control of the total IgE, the immunoglobulins E involved in allergy, remains still unclear. Although high IgE levels were found to be determined by a recessive major gene in several studies, other modes of inheritance were also reported. Moreover, at least two different genetic mechanism