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A Macromolecular Multicomponent Peptide Vaccine Prepared Using the Glutaraldehyde Conjugation Method with Strong Immunogenicity for HIV-1

✍ Scribed by Kenji Hamajima; Hiroki Bukawa; Jun Fukushima; Susumu Kawamoto; Tamiko Kaneko; Ken-Ichiro Sekigawa; Shun-Ichi Tanaka; Mamoru Tsukuda; Kenji Okuda


Book ID
112240738
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
362 KB
Volume
77
Category
Article
ISSN
1090-2341

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Strong immunogenicity of a multicomponen
✍ Kenji Okuda; Tamiko Kaneko; Tadashi Yamakawa; Shunichi Tanaka; Takashi Shigemats 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 900 KB

## Abstract We synthesized one V3 peptide each from HTLV‐III~B~, Thai A and Thai B, conjugating then to the T cell epitope of the __env__ region, and we also synthesized a p17 protein peptide of the __gag__ region (HGP‐30). These peptide were then coupled to 8‐lysine copolymers using __N__‐succinim