A macrocyclic receptor for the chiral recognition of hydroxycarboxylates

✍ Scribed by Antonio Tejeda; Ana I Oliva; Luis Simón; Manuel Grande; Ma Cruz Caballero; Joaquı́n R Morán

• Book ID: 104210414
• Publisher: Elsevier Science
• Year: 2000
• Tongue: French
• Weight: 155 KB
• Volume: 41
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)00693-6

✦ Synopsis

Good chiral recognition of hydroxycarboxylates such as lactic or mandelic acids has been achieved with a macrocyclic receptor, readily available from a known bis-chromenylurea and a spirobi¯uorene linker. Resolution of the receptor racemic mixture was carried out taking advantage of its complexing properties with (R)-mandelic acid tetramethylammonium salt on a TLC plate.