A lower dose of thalidomide is better than a high dose in metastatic renal cell carcinoma
β Scribed by Sandy Srinivas; Alice E. Guardino
- Book ID
- 109051952
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 75 KB
- Volume
- 96
- Category
- Article
- ISSN
- 1464-4096
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Background: The highly vascular nature of renal cell carcinoma (rcc) suggests that angiogenesis inhibition may be therapeutic for patients with this disease. thalidomide inhibits basic fibroblast growth factor and vascular endothelial growth factor (vegf)-induced angiogenesis. ## Methods: In a
## Abstract ## BACKGROUND Metastatic renal cell carcinoma (RCC) has modest response rates to chemotherapy with gemcitabine and 5βfluorouracil (5βFU). Fixed dose rate gemcitabine infusion leads to enhanced intracellular accumulation of drug and possible augmented clinical effect. To determine the t