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A Loss-of-Function Model for Cystogenesis in Human Autosomal Dominant Polycystic Kidney Disease Type 2

✍ Scribed by Roser Torra; Cèlia Badenas; José L. San Millán; Laureano Pérez-Oller; Xavier Estivill; Alejandro Darnell


Book ID
117852929
Publisher
American Society of Human Genetics
Year
1999
Tongue
English
Weight
313 KB
Volume
65
Category
Article
ISSN
0002-9297

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Hepatic cysts are a major manifestation of autosomal dominant polycystic kidney disease. This study examined 239 autosomal dominant polycystic kidney disease patients and 189 unaffected family members to define the factors that influence the presence and severity of hepatic cysts. Autosomal dominant