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A local mechanism generates saturation in an in silico model of in vitro multicellular tumor spheroid growth

✍ Scribed by Jesse A. Engelberg; C. Anthony Hunt


Book ID
113696660
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
92 KB
Volume
22
Category
Article
ISSN
0883-9441

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## Abstract The growth of multicellular tumor spheroids, MTSs, from squamous carcinoma line MDA 886Ln was inhibited by β‐all‐trans retinoic acid (RA). Inhibition occurred within 3 to 5 days of treatment, and MTS size then remained static for up to 2 weeks. Although their growth stopped, 10‐day‐trea