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A liquid chromatography/tandem mass spectrometry method for determination of aristolochic acid-I in rat plasma

✍ Scribed by Yiming Liu; Aihua Lin; Zhifeng Wu; Runmei Ou; Haiding Huang


Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
236 KB
Volume
24
Category
Article
ISSN
0269-3879

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## Abstract A rapid, sensitive and selective liquid chromatography–tandem spectrometry method was developed and validated for determination of paeoniflorin in rat plasma using geniposide as the internal standard. The samples were pretreated with solid‐phase extraction using Extract‐Clean™ cartridge