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A link between the p53 germ line polymorphisms and white blood cells apoptosis in lung cancer patients

✍ Scribed by Biroš, Erik; Kohút, Anton; Biroš, Ivan; Kalina, Ivan; Bogyiová, Eva; Štubňa, Ján


Book ID
118570749
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
87 KB
Volume
35
Category
Article
ISSN
0169-5002

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Mutations of the p53 tumor suppressor gene are frequent in lung cancers. It is suggested that p53 mutations are associated with smoking-induced lung carcinogenesis. We examined p53 mutations in 53 lung cancers by analyzing reverse transcription-polymerase chain reaction-single strand conformation po