A Lignoid Glycoside and Dimeric Phenylpropanoids from Daphne oleoides

✍ Scribed by Nisar Ullah; Prinz Sonja; Ernst Haslinger; Wagar Ahmed; Mohammed Arfan; Abdul Malik

• Publisher: John Wiley and Sons
• Year: 2001
• Tongue: German
• Weight: 88 KB
• Volume: 84
• Category: Article
• ISSN: 0018-019X
• DOI: 10.1002/1522-2675(20010131)84:1<157::aid-hlca157>3.0.co;2-#

✦ Synopsis

Three new natural products, a lignoid glycoside 1 and two dimeric phenylpropanoids 2 and 3, along with two known lignans 4 and 5, were isolated from the BuOH-and CHCl 3 -soluble fractions of the whole plant of Daphne oleoides (Thymelaeaceae). The structures of the new compounds were established by spectroscopic techniques, including 2D NMR, as 4-(b-d-glucopyranosyloxy)-9'-hydroxy-3,3',4'-trimethoxy-7',9-epoxylignan (1), (1R,2S,5R,6R)-6-(3-ethyl-4-hydroxy-5-methoxyphenyl)-2-(4-hydroxy-3,5-dimethoxyphenyl)-3,7-dioxabicyclo-[3.3.0]octane (2) and (1R,2S,5R,6S)-2,6-bis(3-ethyl-4-hydroxy-5-methoxyphenyl)-3,7-dioxabicyclo[3.3.0]octane (3). The other lignans were identified as ()-pinoresinol O-(b-d-glucopyranoside) (4) and ()-medioresinol (5).