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A lentiviral vector expressing a fusogenic glycoprotein for cancer gene therapy

✍ Scribed by Diaz, R M; Bateman, A; Emiliusen, L; Fielding, A; Trono, D; Russell, S J; Vile, R G

Book ID
110038766
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
518 KB
Volume
7
Category
Article
ISSN
0969-7128

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## Abstract ## Background Malignant glioma has a dismal prognosis. It was previously shown that glioma cells are efficiently killed when they express a gene coding for a hyperfusogenic mutant of the gibbon ape leukemia virus envelope glycoprotein (GALV.fus). However, production of viral vectors ex